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To the TTU Financial Aid Office at 806.742.3681.įor more information about Hire Red Raiders, please reach out to the TTU Career Center ![]() Job Posting Boardsįor more information about TTU Human Resources - Student Positions, please reach outįor more information about Red Raider Student Employment Center, please reach out If you are needing support in identifying options, set up an appointment on Hire Red Raiders and schedule an appointment online! If you have any questions navigating the site, Scribe/Readers may work with students in classes and/or during tests. Most work will be on-ground there will be minimal remote opportunities. Pages for departments that typically hire students. Bellevue, WA 98007 (Eastgate area) 14.49 an hour. 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![]() It's up to you to choose the intensity of each session.The app doesn't have much depth at the end of the day.Replacement parts are fairly affordable.I think most of you probably have a good grasp of what my conclusion will be, but as usual, let's go over the pros and cons before making any final calls. But your number one concern should be to get the proper technique down. This doesn't mean there aren't better brushes in the market. So someone with a high-end brush but poor technique and someone with amazing technique and a $5 brush will experience similar results. Turns out a lot of us aren't as great at brushing as we'd like to believe. But the general response is that the features of a brush don't matter anywhere near as much as your technique. And cheaper brands don't offer as much quality. Bristles should be firm to provide better cleaning. Of course, certain criteria are consistent across most recommendations. Most dentists I've talked to aren't particularly concerned about the brand or model of brush you pick. However, the common answer might shock you. After all, if anybody knows what makes a good brush is a dentist. Something that I like to ask all dentists I come across is what brush do they recommend. So here's the thing, I'm not a dental expert, but I've talked to a fair amount. On top of that, the Quip has a very similar design to the Foreo when it comes to the bristles so you get the same level of gum comfort. The vibrations are firm and consistent without being painful, and since the brush is so minimalistic the grip is just perfect. Honestly, it likely won't add much unless you use the brush for kids, but it's way better than a lot of alternatives in the market.Īs for the brushing experience itself, it is really good. Rather the app is more of short tutorials and tracker for your brushing. You don't need the app to unlock or turn on your brush at all. The App however is way less intrusive than any of Foreo's attempts on the subject. The key differences with the Issa are that there are no intensity settings and that the Quip comes with an app. The Quip Brush comes apart rather easily and it thankfully uses regular batteries to work. Quip offers you battery and head replacements for basically $5 a month, but thankfully that's not the only option. In what has to be the most unique design choice with this brush there isn't even a charger. Once you open the $65 package you'll come across your new brush, a small tube base and that's it. If the Foreo Issa 2 was straightforward then the Quip Smart Electric Toothbrush is downright minimalistic. It's a simple trick, but it is clever and I love how it feels on my mouth. This means you can get solid bristles for your teeth and a soft sensation on your gums at the same time. The head of the brush uses both traditional bristles on the middle and much softer silicone ones on the edges. Thankfully once you start brushing you do start to notice how smart its design is. The Issa 2 has 16 intensities that you can easily regulate with the "+" and "-" buttons, but beyond that, it works like any other toothbrush in the market. So the feeling on my teeth is the most important aspect to consider. There are no alternate head attachments, no charging base, no tricks or whistles. You get the brush itself, a USB charge cable, and a travel pouch. The Issa 2 on the other hand is focused on oral hygiene and works perfectly well without an app.ĭespite the price tag of $169 the Foreo Issa 2 comes with the bare essentials. If you've seen past reviews of Foreo products then you probably are aware of their extensive skincare line, and the fact that they rely very heavily on apps. The Foreo Issa 2 was something of a surprise to me. But beyond the Foreo Issa 2 vs Quip comparison, I also want to teach you some secrets to the world of oral hygiene, so you can finally have the perfect teeth you've dreamed of. I'll show you two unique electric toothbrushes that have a lot of reputation and support online: The Foreo Issa 2 and the Quip Smart Electric Toothbrush. Today I'll be focusing on that last aspect. People argue all the time about what's the right way to brush your teeth, the right toothpaste to use, and of course most important of all, which is the one brush to rule them all. I've always liked to believe that my oral hygiene is up to par, but there's no denying that there are a lot of angles to consider. Whether you are a woman, a man, or a kid your teeth will always matter and will always need care. If there's one aspect of our healthcare that seems to be a universal constant that has to be our teeth. While the Issa 2 has more functions integrated, you can expect similar results from these two devices. Designed as luxury toothbrushes both the Foreo Issa 2 and Quip Smart Electric Toothbrush share similar design ideologies. close will close this PR and stop Dependabot recreating it.From import Keys.947284e Improve message for ProxySchemeUnknown exception.a800c74 Recommend GitHub Sponsors instead of Open Collective.cb5e2fc Don't compare bytes and str in putheader().d97e5d4 Use Python 3.5 compatible get-pip.3179dfd Allow using deprecated OpenSSL with CRYPTOGRAPHY_ALLOW_OPENSSL_102.More actionable if the user supplies a proxy URL without 1.26.3 ()Ĭhanged ProxySchemeUnknown error message to be Release notesįixed bytes and string comparison issue with headers (Pull #2141)Ĭhanged ProxySchemeUnknown error message to be more actionable if the user supplies a proxy URL without a scheme (Pull #2107) 5e34326 Add proper stacklevel to method_allowlist warningīumps urllib3 from 1.26.2 to 1.26.3.8d65ea1 Merge pull request from GHSA-5phf-pp7p-vc2r.The default SSLContext now sets check_hostname=True. Changed behavior of the default SSLContext when connecting to HTTPS proxyĭuring HTTPS requests.Changed behavior of the default SSLContext when connecting to HTTPS proxy during HTTPS requests.dependenciesīumps urllib3 from 1.26.3 to 1.26.4. You can disable automated security fix PRs for this repo from the Security Alerts page. use this milestone will set the current milestone as the default for future PRs for this repo and language.use these assignees will set the current assignees as the default for future PRs for this repo and language.use these reviewers will set the current reviewers as the default for future PRs for this repo and language.use these labels will set the current labels as the default for future PRs for this repo and language.ignore this dependency will close this PR and stop Dependabot creating any more for this dependency (unless you reopen the PR or upgrade to it yourself).ignore this minor version will close this PR and stop Dependabot creating any more for this minor version (unless you reopen the PR or upgrade to it yourself).ignore this major version will close this PR and stop Dependabot creating any more for this major version (unless you reopen the PR or upgrade to it yourself).You can achieve the same result by closing it manually ![]() close will close this PR and stop Dependabot recreating it.reopen will reopen this PR if it is closed.cancel merge will cancel a previously requested merge and block automerging.squash and merge will squash and merge this PR after your CI passes on it.merge will merge this PR after your CI passes on it.recreate will recreate this PR, overwriting any edits that have been made to it.You can trigger Dependabot actions by commenting on this PR: You can also trigger a rebase manually by commenting rebase. 1884878 Properly proxy EOF on the SSLTransport test suiteĭependabot will resolve any conflicts with this PR as long as you don't alter it yourself.d725a9b Add Python 3.10 to GitHub Actions.07bed79 Fix deprecation warnings for Python 3.10 ssl module.2d4a3fe Improve performance of sub-authority splitting in URL.Improved performance of URL parser when splitting.If you or your organization rely on urllib3 consider supporting us via GitHub Sponsors Changelog Improved performance of URL parser when splitting the authority component.Updated vendored six library to 1.16.0. ![]()
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Several of the pathological outcomes in ATM deficient mice have been linked to ROS and many of these pathologies can be reversed by the addition of antioxidants, highlighting the important role of ATM in regulating redox-homeostasis (Ito et al., 2004 Reliene and Schiestl, 2006, 2007 Reliene et al., 2008 Freund et al., 2011 Okuno et al., 2012 D'Souza et al., 2013). Aside from increased tumorigenesis, ATM-deficiency results in altered metabolism, aberrant immune and inflammatory responses and increased levels of reactive oxygen species (ROS, Schneider et al., 2006 Alexander et al., 2010 Freund et al., 2011 Kulinski et al., 2012 Valentin-Vega et al., 2012). Thus, tumor suppressive or promoting activities from the same protein can be dictated by many factors including mutations, cell type, and/or disease context.ĪTM regulates complex signaling networks that are involved in many biological processes in addition to DSB signaling and repair (Stracker et al., 2013). However, the tumor-associated gain-of-function p53 mutations that are most commonly observed in human cancers exhibit several tumor-promoting functions (Muller and Vousden, 2013). This concept is perhaps best exemplified by p53, which is normally activated by stress signals and promotes tumor suppressor pathways (Bieging et al., 2014). Thus, DDRs can influence both cancer promoting and suppressing mechanisms. Defects in the DDR can also profoundly influence DNA damage-dependent therapies both positively and negatively (Bouwman and Jonkers, 2012). Cancer cells evolve a defective DDR to allow cell proliferation in the presence of DNA damage, furthering genome instability and cancer progression. However, cancer cells exhibit genome instability (Hanahan and Weinberg, 2011) and often contain endogenous oxidative and replicative damage that can promote genetic alterations to drive malignant transformation (Klaunig et al., 2010 Hills and Diffley, 2014). Many of these pathways depend on ATM and/or p53 to enforce tumor suppressive anti-cancer barriers to limit proliferation in response to, and in the presence of, DNA damage (Norbury and Zhivotovsky, 2004 Bartkova et al., 2005 Gorgoulis et al., 2005 Bartkova et al., 2006 Di Micco et al., 2006 Vousden and Lane, 2007 Sherman et al., 2011 Roos and Kaina, 2013). The DDR regulates cell fate decision pathways including apoptosis, senescence and differentiation. ![]() ![]() The apical protein kinase ataxia-telangiectasia mutated (ATM) initiates a large signaling cascade in response to DNA double-strand breaks (DSBs) by phosphorylating many key proteins, including the tumor suppressor p53, to orchestrate the DDR (Shiloh and Ziv, 2013 Stracker et al., 2013). These cancer therapies activate complex signaling networks, termed the DNA damage response (DDR), that detect and signal the presence of DNA damage to promote cell cycle arrest and DNA repair (Jackson and Bartek, 2009 Ciccia and Elledge, 2010). Cancer treatments rely heavily on DNA damaging agents, including radiation and chemotherapeutics, to eliminate cancer cells and decrease tumor burden (Begg et al., 2011 Lord and Ashworth, 2012 Cheung-Ong et al., 2013). So…how best to approach our Coloring Tribe and to not miss anymore FREE coloring pages in the future?įirst… if you have not yet done so… JOIN our Coloring Tribe on Facebook and show off your colored creations. All coloring pages are completely free to download. You will find many of your favorite Halloween characters and images: Halloween pumpkins, scary monsters, mummy, vampire, haunted houses, cats, scarecrows, bats, witches and. 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On the other hand, uncircumcised women risk being treated as men their funeral and burial rites may be performed as if they are men because the presence of the clitoris makes a woman masculine. The belief is that circumcised girls can be trained on societal morals and values before they assume a larger role in the community as wives and mothers. They are taught how to care for their families, homes, and uphold themselves in the community. In some societies, circumcised girls receive mentorship to prepare them for marriage and meaningful lives. In some communities, the practice is tied to traditional religion and in others, it is associated with Islam. Some studies reported that traditions and social norms pressure girls to undergo circumcision: women who are not circumcised often experience ridicule from peers and rivals. Higher occurrence of FGM in Northern Ghana has been attributed to the mixture of the people and culture of that part of the country with Burkina Faso, Togo and Mali, where the practice is more common. ![]() England and the United States used FGM to treat hysteria, lesbianism, masturbation and other female deviances in the 1940s and 1950s. Historical antecedents and social research revealed that FGM was practiced by the Phoenicians, Hittites and ancient Egyptians. FGM has been in existence for many years, but it only generated international activism when it was widely discussed in the nineteen-eighties and early nineteen-nineties. In the Bawku Municipality and Pusiga District, sixty one percent of women were reported to have undergone the procedure. FGM is predominately practiced among the northern tribes of Ghana and the magnitude of the practice varies across regions and districts. Globally, an estimated two million women are circumcised and four percent of those genitally mutilated live in Ghana. The practice occurs in 28 African countries with varying prevalence within and across countries. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.Ĭompeting interests: The authors have declared that no competing interests exist.įemale Genital Mutilation (FGM) is deeply ingrained in many African societies. Thus, the Female Genital Mutilation project data are available upon request from the Navrongo Health Research Centre IRB Administrator: Cletus Tindana ( Research reported in this publication was supported by the Fogarty International Center of the National Institutes of Health under Award Number D43TW009345. ![]() The Navrongo Health Research Centre Institutional Review Board (NHRCIRB) has restricted the sharing of these data publicly because the data contain sensitive participant information. The work is made available under the Creative Commons CC0 public domain dedication.ĭata Availability: The data used in this study come from the Female Genital Mutilation study, whose authors are affiliated with the Navrongo Health Research Centre. This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. Received: JAccepted: MaPublished: April 22, 2019 PLoS ONE 14(4):Įditor: Yeetey Akpe Kwesi Enuameh, Kwame Nkrumah University of Science and Technology, GHANA Citation: Sakeah E, Debpuur C, Aborigo RA, Oduro AR, Sakeah JK, Moyer CA (2019) Persistent female genital mutilation despite its illegality: Narratives from women and men in northern Ghana. |